Themen für Bachelorarbeiten

Beschreibung: Posttraumatic stress disorder (PTSD) and substance abuse (SUD) share key mechanistic similarities in terms of underlying learning and memory mechanisms, so that one disorder could effectively «prime» development of the other, hence making patients in recovery from PTSD more susceptible to SUD and vice versa. A highly emotional event initiates memories perceived as sudden and uncontrollable. Few studies have investigated this pathological memory process with a script guided imagery approach in fMRI but also psychophysiological measures. This bachelorthesis will review studies on common and distinct findings in PTSD and SUD studies using a script guided imagery approach.
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Eingabedatum: 12.01.2023
Kontakt: Lina Dietiker, E-Mail

Beschreibung: Posttraumatic stress disorder (PTSD) and substance abuse (SUD) share key mechanistic similarities in terms of underlying learning and memory mechanisms, so that one disorder could effectively ?prime? development of the other, hence making patients in recovery from PTSD more susceptible to SUD and vice versa. Few studies have investigated overlap in intrusive emotional memories in these disorders, i.e., intrusive trauma memories in PTSD and drug memories/ craving in SUD. This bachelorthesis will review studies on common and distinct characteristics in PTSD and SUD, including their frequency and timing of these memories. This will include self-report questionnaire and clinical interview data, as well as daily diary approaches in patients. An additional bachelorthesis will review recent empirical evidence on modulation strategies for such memories, including reconsolidation blockage. Vogel L, Koller G, Ehring T. The relationship between posttraumatic stress symptoms and craving in patients with substance use disorder attending detoxification. Drug Alcohol Depend. 2021 Jun 1;223:108709. doi: 10.1016/j.drugalcdep.2021.108709.
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Eingabedatum: 09.07.2021
Kontakt: Lina Dietiker, E-Mail

Beschreibung: Schlaf ist ein sehr aktiver Prozess in Bezug auf die Veränderung von Gedächtnisprozessen. Im Schlaf werden Erinnerungen reaktiviert, mit bereits bestehenden Erinnerungen integriert. Weiterhin wird der affektive Anteil von Erinnerungen abgebaut. Diese Prozesse gelten v.a. auch für emotionale Erinnerungen. Grundlagenwissenschaftliche Studien konnten zeigen, dass diese Reaktivierung experimentell steuerbar ist, z.B. durch Präsentation von Düften oder Wörtern, die während bestimmter Erinnerungen anwesend waren. Die vorliegende BA Arbeit identifiziert und fasst entsprechende Studien zusammen und soll die Effektivität und Anwendbarkeit für die Psychotherapie prüfen.
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Eingabedatum: 25.08.2021
Kontakt: Dominique Recher, E-Mail

Beschreibung: Even though it has been established that sleep plays an important role in the consolidation of fear memory, it is not clear whether sleeping directly after experiencing a negative or traumatic event is decreasing or increasing the risk of developing a post-traumatic stress disorder (PTSD). Answering this question is especially interesting in the context of PTSD treatment. Since there is a lot of contrasting evidence for both hypothesis, this bachelor thesis will review recent studies investigating the effect of sleep on fear memory consolidation and potentially aim to find underlying commonalities in studies which show a beneficial effect of sleep on fear memory extinction and lastly may give an outlook to potential studies improving inference of this questions.
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Eingabedatum: 04.02.2021
Kontakt: Jelena Wehrli, E-Mail

Beschreibung: Die Befragung von psychiatrischen Patienten zur Zufriedenheit mit ihrem stationären Aufenthalt hat in den letzten Jahren zunehmend an Bedeutung gewonnen. Im Rahmen von Massnahmen zur Qualitätssicherung können durch die Befragungen viele wichtige Informationen gesammelt werden, welche von der Zufriedenheit mit dem klinischen Alltag bis hin zur Zufriedenheit mit der Hotellerie reichen. Studien haben gezeigt, dass Patientenzufriedenheit auch stark mit klinischen Faktoren assoziiert ist, wie z.B. der Schwere einer psychischen Erkrankung (Psychopathologie, Diagnose) und auch dem Behandlungserfolg oder Rehospitalisierungsrisiko. Auf der anderen Seite unterliegt Patientenzufriedenheit konsistent gewissen soziodemographischen Trends wie z.B. alters- und geschlechtsspezifischen Zusammenhängen. Die Heterogenität der wissenschaftlichen Befunde zeigt jedoch, dass die dabei zugrunde liegenden Mechanismen sehr komplex und Kausalitäten noch nicht vollständig geklärt sind. Ziel der geplanten Arbeit soll es sein, aus der Vielzahl der Ergebnisse einen Überblick über den aktuellen Stand der Forschung zu erstellen, um die Bedeutung und komplexe Assoziation von Patientenzufriedenheit im klinisch-psychiatrischen Kontext theoretisch zu modellieren. Hannöver, W., Dogs, C. P., & Kordy, H. (2000). Patientenzufriedenheit?ein Maß für Behandlungserfolg?. Psychotherapeut, 45(5), 292-300. Modestin, J., Hanselmann, F., Rüsch, P., Grunwald, H., & Meyer, P. (2003). Der Zurcher Fragebogen zur Patientenzufriedenheit in der Psychiatrie: Entwicklung und Charakteristika. Archives Suisses de Neurologie et de Psychiatrie, 154(3), 127-138. Woodward, S., Berry, K., & Bucci, S. (2017). A systematic review of factors associated with service user satisfaction with psychiatric inpatient services. Journal of psychiatric research, 92, 81-93.
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Eingabedatum: 14.07.2020
Kontakt: Dr. phil Mario Müller, E-Mail

Beschreibung: Even though many think that memories are permanent and cannot be changed or erased, research suggests otherwise. There is a lot of evidence that memories can be altered through pharmacological or behavioral interventions, sometimes profoundly, when they are recalled. This is especially interesting in the context of post-traumatic stress disorder, where people suffer from recurring emotion-laden memories of the traumatic event, so called intrusive memories. This bachelor thesis will review recent studies on interventions that block reconsolidation. It will discuss which interventions are used in clinical practice, in experimental studies with an analog trauma model and suggest further interventions.
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Eingabedatum: 16.01.2020
Kontakt: Laura Meister, E-Mail

Beschreibung: Sleep difficulties, sleep disorders as well as changes in psychophysiological sleep mechanisms, such as alterations in sleep depth or REM pressure, are associated with psychopathological symptoms and/or mental disorders (e.g. Baglioni et al., 2017) as well as reduced well-being and functioning (e.g. Hirshkowitz et al., 2015). The improvement of sleep quality and quantity therefore often represents an important therapeutic target in the treatment of mental disorders and/or the improvement of well-being. In addition, there is increasing empirical evidence that psychophysiological sleep mechanisms can be influenced in both healthy and people suffering from mental illnesses in order to improve human functioning such as cognitive and memory functions (e.g. Schouten, Pereira, Tops, & Louzada, 2017) and sleep can even improve psychotherapeutic outcomes (e.g. Kleim et al., 2016). The goal of this bachelor thesis is to review the current evidence on how sleep can influence and improve psychotherapeutic outcomes. In particular, a review of studies that a) investigate sleep as a means to enhance therapeutic effects and b) a summary of the various hypotheses proposed regarding the mechanisms by which sleep enhances therapeutic effects is part of the thesis. The thesis can be written in German or English.
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Eingabedatum: 16.01.2020
Kontakt: Dominique Recher, E-Mail

Beschreibung: Smartphones have become ubiquitous in our daily lives, with over three billion people worldwide owning one. The processing power of each single mobile device nowadays is comparable to the capacities of super-machines of the early 90?s. Accompanying smartphones, numerous smartwatches and other smart-wearables offer to boost our physical performance, sleep quality, and mental health?and are thus also frequently used. Altogether, large amounts of highly resolved data can be collected from these digital devices. People?s activity, location trajectories, social engagement, physiological data, sleep patterns, as well as cognitive and behavioral traits can be tracked in real-time, in an ecological and objective fashion. This is referred to as digital phenotyping, and offers itself as a powerful tool in psychiatry (Insel, 2018). The advances in big data processing and artificial intelligence have enabled it to reveal individual fingerprints of neurocognitive function and mood state based on such digitally acquired data. Early warnings of mental illness and crises can be derived from digital phenotyping features and facilitate adequate interventions. Thus, the application of digital phenotyping and mobile sensing holds great potential to be applied in clinical setting. The aim of this thesis is to review the methods and applications of digital phenotyping and mobile sensing in mental health, with a special focus on suicidal behavior. The thesis would delineate digital phenotyping features that have been shown to be most informative in suicidal behavior monitoring, and how they relate to cognitive function and clinical symptoms. The thesis would also summarize and scrutinize currently offered mobile phone applications that use digital phenotyping markers to improve the procedures in suicidal behavior monitoring and interventions.
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Eingabedatum: 16.01.2020
Kontakt: Dr. Anja Ries, E-Mail

Beschreibung: Psychotherapy is effective for the treatment of a number of psychiatric conditions. However, a common belief is that psychotherapy might not be beneficial for all patients. How can we determine if this belief is justified? N-of-1 trials allow answering this question (Senn, 2018). With these single-patient, multiple cross-over trials, the effect of the treatment of interest (e.g. psychotherapy) can be systematically assessed and compared with the effect of other treatments and/or placebo. Thus, n-of-1 trials provide a sophisticated method to identify the optimal treatment for an individual patient. The associated bachelor thesis should be aimed at summarizing the current literature on n-of-1 trials in psychotherapy and behavioral interventions. In particular, the specifics of the included trials (e.g. which interventions were compared) should be highlighted and compared. Finally, the trial’s results should be discussed to answer the question whether or not psychotherapy was beneficial (or harmful) to the respective patient.
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Beschreibung: tress-related disorders are common and affect a large number of individuals around the globe. Understanding who develops stress-related disorders and who succumbs to stress is therefore paramount. One factor identified as a predictor of resilience is extinction recall in the context of aversive memories. Specifically, extinction refers to a reduction in conditioned responses for negative stimulus and is thought to form a new safety memory. This bachelor thesis will review recent studies that help understand better underpinning processes of acquisition and recall of extinction, as well as their impact on resilience. Such mechanisms may be found in behavioural experiments, as well as in studies involving physiological measurements, neuroimaging, neurotransmitters and hormones levels.
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Beschreibung: Even though many think that memories are permanent and cannot be changed or erased, research suggests otherwise. There is a lot of evidence that memories can be altered through pharmacological or behavioral interventions, sometimes profoundly, when they are recalled. This is especially interesting in the context of post-traumatic stress disorder, where people suffer from recurring emotion-laden memories of the traumatic event, so called intrusive memories. This bachelor thesis will review recent studies on interventions that block reconsolidation. It will discuss which interventions are used in clinical practice, in experimental studies with an analog trauma model and suggest further interventions.
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Beschreibung: Experiencing recurring emotion-laden aversive memories of the event is the hallmark symptom of post-traumatic stress disorder (PTSD). In certain ways PTSD can be seen as a memory disorder. Within our brain, memory storage and memory retrieval are heavily influenced by both time of day (thanks to an endogenous circadian clock) and sleep pressure (through a homeostatic sleep-wake mechanism). Thus, it is probable that the development as well as the recurring symptoms of intrusive memories are heavily influenced by chronobiology. This thesis will review studies to answer the question whether chronobiological factors, such as indices relating to the circadian clock, are associated with changes in trauma memory and whether this has been related to emotional memory changes in psychotherapy. Such a link could be meaningfully exploited for memory modulation and optimizing current psychotherapy for PTSD.
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Beschreibung: Understanding suicidal ideation, as well as predicting, and preventing suicide is currently in its infancy. New methods, such as ecological momentary assessments or streams of data from smartphone sensors (e.g. GPS) and wearables (e.g. heart rate) offer new was to monitor and, possibly, intervene as processes unfold in real-time. This thesis will review recent studies and investigate predictors of suicidal ideation, including those that can be obtained in real life. Such monitoring methods may create new opportunities for scientific and clinical advances.
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Beschreibung: A growing body of literature reports significant and consistent associations between sleep disturbances and suicidal ideation and suicidality. Prospective studies have assigned a seminal role to sleep disturbances and nightmares in predicting suicidality (e.g. Nadorff, Nazem, & Fiske, 2011). This bachelor thesis will review recent studies and identify, whether current evaluation of psychological treatments of suicidality included (i) an assessment of sleep and/or (ii) sleep as part of a psychological treatment module.
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Beschreibung: Individuals’ reactions and psychological functioning in response to a potentially traumatic event (PTE) have been classified as several distinct outcome groups. These analyses have repeatedly identified resilience as the largest response group. Resilience has been defined as no disturbance or relatively quick recovery after exposure to a PTE. Who is resilient and who succumbs to stress? Evidence in terms of predictors for resilient responding is mixed. This bachelor thesis will review recent studies on predictors of resilient outcome across different groups, i.e., spousal or child loss, disease, military trauma or police deployment.
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Beschreibung: There is increasing scientific evidence pointing towards the key influence of innate biological rhythms, such as the circadian rhythm, on disease onset and progression. Part of the mechanisms for this may be accounted for by the bidirectional link between circadian rhythms and the immune system. In fact, disruption of these cycles have been shown to contribute to changes in pathology, including changes in fatigue, and mood. This thesis will review studies to answer the question whether chronobiological factors, such as indices relating to the circadian clock, are associated with changes in emotional memory and whether this has been related to emotional memory change in psychotherapy. Such a link could be meaningfully exploited to enhance learning, memory modulation and optimise current psychotherapy.
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Beschreibung: Ob eine Geburt, welche in der Regel ein vorhersehbares Ereignis ist, eine PTBS hervorrufen kann, wurde immer wieder kontrovers diskutiert. Die in den letzten Jahren zunehmende Anzahl an Studien konnte zeigen, dass ein Drittel der Frauen die Geburt ihres Kindes als traumatisch beschreibt und dass die Raten an PTBS nach Geburt bei Frauen ohne PTBS vor der Geburt bei knapp 5 % liegen. Natürlich haben nicht alle Gebäenden das gleiche Risiko eine PTBS zu entwickeln. Das Ziel dieser Bachelorarbeit ist die Analyse und Zusammenfassung der aktuellen Literatur zu den Risikofaktoren für die Entwicklung einer postpartalen PTBS.
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Beschreibung: Die Untersuchung von posttraumatischem Stress nach Geburt stiess in den letzten auf zunehmendes Interesse (s. o.). Dennoch sind viele Aspekte noch nicht gänzlich verstanden und es gibt soweit keine klaren Empfehlungen bezüglich Prävention, Frühintervention und psychotherapeutischer Behandlung. Das Ziel dieser Bachelorarbeit ist die Analyse und Zusammenfassung der aktuellen Literatur zu Prävention und Behandlung von postpartaler PTBS.
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Beschreibung: Healthy sleep may promote resilience in the face of stress and adversity. Most previous studies that assess this association rely on laboratory measures or retrospective questionnaires. There are some studies, however, that have investigated this relationship by collecting prospective data on the association between sleep and resilience using real-time objective assessments. These studies help to shed light on the daily relationship and interactions of sleep and stress related variables. The present BA thesis aims to analyze and summarize current literature on ecological momentary/EEG and actigraphy data and stress responses to investigate whether sleep is associated with reduced psychopathology in the face of adversity.
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Beschreibung: Schlaf ist ein sehr aktiver Prozess in Bezug auf die Veränderung von Gedächtnisprozessen. Im Schlaf werden Erinnerungen reaktiviert, mit bereits bestehenden Erinnerungen integriert. Weiterhin wird der affektive Anteil von Erinnerungen abgebaut. Diese Prozesse gelten v.a. auch für emotionale Erinnerungen. Grundlagenwissenschaftliche Studien konnten zeigen, dass diese Reaktivierung experimentell steuerbar ist, z.B. durch Präsentation von Düften oder Wörtern, die während bestimmter Erinnerungen anwesend waren. Die vorliegende BA Arbeit identifiziert und fasst entsprechende Studien zusammen und soll die Effektivität und Anwendbarkeit für die Psychotherapie prüfen.
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Beschreibung: Suizidalität stellt in der Schweiz wie international ein grosses soziales wie ökonomisches Problem dar. Empfehlungen aktueller Leitlinien zur psychotherapeutischen Behandlung sind bisher jedoch vage und es bestehen keine klaren Empfehlungen zur psychotherapeutischen Behandlung. Einige Studien haben jedoch inzwischen einige Programme entwickelt, adaptiert, sowie untersucht. Die Bachelorarbeit soll diese aktuelle Literatur zu evidenzbasierten psychotherapeutischen Therapieprogrammen zur Behandlung von Suizidalität identifizieren und hinsichtlich ihrer Effektivität evaluieren.
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Beschreibung: Im Feld der Ökonomie werden Nudges schon seit längerem erforscht und in der Praxis eingesetzt. Obwohl das Konzept aus der Verhaltensökonomie noch jung ist, gibt es schon viele Beispiele aus Wirtschaft und Politik. Auch in anderen Bereichen kann das Prinzip helfen, beispielsweise in der Psychotherapie. Dort ist die Translation und Umsetzung gelernter neuer Inhalte essentiell, genau an dieser Stelle scheitern jedoch viele Psychotherapeuten. Könnten Nudges im Kontext der Psychotherapie verwendet werden, um Patienten bei der besseren Umsetzung des Gelernten in den Alltag zu unterstützen? In der Masterarbeit sollen Studien identifiziert und zusammengefasst werden, die Nudges Kontexten untersucht haben, die für die Psychotherapie relevant sind.
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Beschreibung: Neuere psychologische Psychotherapien beinhalten transdiagnostische Protokolle. Psychotherapeuten können hier mittels einzelner Module, die zum Teil individuell und entsprechend der Symptomkonstellatio der Patienten, zusammengestellt werden. Somit können Patienten mit unterschiedlichen Störungen behandelt werden (anstatt mit störungsspezifischen Manualen für unterschiedliche Störungen zu arbeiten). Die Bachelorarbeit soll anhand aktueller Literatur die Effektivität transdiagnostischer Therapien untersuchen, mit Fokus auf langfristigen Effekten auf Symptome der Psychopathologie.
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Beschreibung: During the course of a normal life span, most of us will incur stressful or traumatic events, such as a car accident, an assault, the loss of a partner or close friend etc. Exposure to such events can result in disabling mental health problems, such as anxiety disorders or depression. However, there is great individual variability in psychological responding to trauma. Even when exposed to extreme stressors, many individuals do not develop enduring psychopathological responses, and display relatively good psychological outcome. Why are some individuals resilient in this manner, while others succumb to stress? The present theses aims to investigate current literature to identify predictors for resilient responding across studies.
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Beschreibung: Increasing perceptions of self-efficacy may promote future thinking and problem solving in ways that are relevant to overcoming trauma and adversity. This study examines current evidence of whether enhancing perceptions of self-efficacy can promote psychotherapy-relevant processes.
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Beschreibung: Positive autobiographical memory retrieval has been linked to well-being. However, there are some inconsistencies in the literature that may partly be due to different definitions and assessment methods of positive autobiographical memories. The current thesis will review how positive autobiographical memory retrieval relates to well-being in the light of different definitions and assessment methods of positive memories.
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Beschreibung: Wie verändern sich Symptome von Depression und Angst bei Patienten mit psychischen Störungen im Verlauf der Behandlung? In dieser Bachelorarbeit sollen methodisch hochwertige Studien mit mehrfachen Veränderungsmessungen gesammelt und überprüft werden, mit Fokus auf Patienten mit depressiven Erkrankungen und Behandlung im tagesklinischen/day-clinic setting. Ziel ist die Zusammenfassung der aktuellen Literatur und Evaluation der Ergebnisse.
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Beschreibung: How get emotional experiences recapitulated during sleep and how does this process influence the formation of our memories? Several studies have examined how specific sleep indices correspond to the manifestation of newly acquired emotional memories. In a process called offline-consolidation, memory networks are reactivated during sleep without any sensory input. The aim of the thesis is to review recent research on the impact of different sleep indices on emotional memory networks and potential clinical applications of these mechanisms.
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Beschreibung: Sleep disturbances including nightmares are common in individuals with various psychiatric disorders. Most of these studies seem to have been conducted in psychiatric inpatients, excluding the more severely afflicted patients that often suffer from comorbid diagnoses and possible additional social and other problems. Furthermore, disorder specificity of the various disturbed characteristics of sleep are not well known. This thesis will review the current literature on the prevalence and charasteristics of sleep disturbances in psychiatric in- and outpatients and discuss implications for psychotherapy.
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Beschreibung: There is increasing scientific evidence pointing towards the key influence of innate biological rhythms, such as the circadian rhythm, on disease onset and progression. Part of the mechanisms for this may be accounted for by the bidirectional link between circadian rhythms and the immune system. In fact, disruption of these cycles have been shown to contribute to changes in pathology, including changes in fatigue, and mood. This thesis will review studies to answer the question whether chronobiological factors, such as indices relating to the circadian clock, are associated with changes in emotional memory and whether this has been related to emotional memory change in psychotherapy. Such a link could be meaningfully exploited to enhance learning, memory modulation and optimise current psychotherapy.
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Beschreibung: Sleep promotes memory consolidation. These consolidation processes include the reactivation and reorganization of earlier acquired memory traces. Understanding these processes is of high relevance for posttraumatic stress psychopathology (e.g. intrusive symptoms). However, the direction of the relationship between sleep and these memory processes is not yet fully understood. The aim of this bachelor project is to review and disentangle the relationship between sleep and emotional memory processing based on recent research.
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Beschreibung: Retrieving positive memories of the personal past has been identified as an adaptive emotion regulation strategy and found to be associated with increased positive affect and mental health. In psychopathology, such as depression, positive autobiographical memory retrieval seems to be less beneficial and key characteristics, e. g. vividness or emotional intensity, seem to be disrupted. This thesis will review the current literature on positive autobiographical memory characteristics in the context of mental health and psychopathology and discuss implications for psychotherapy.
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Beschreibung: It is well documented that many people maintain mental health despite exposure to severe psychological or physical adversity (Bonanno et al., 2011; Chang et al., 2015). Resilience research tries to understand why some people do not, or only temporarily, develop stress-related mental dysfunctions while other individuals succumb to the same kind of challenges. The current thesis will review experimental and naturalistic studies on predictors and possible mechanisms that can protect individuals against stress-related psychopathology.
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